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25 amp. Actovegin rr d / 2ml in.80mg amp. (Kusum Pharm). Free shipping (1)

 
 
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INSTRUCTION
medical use of the drug
Actovegin
Title of Commerce
Actovegin
Latynskoe Title
ACTOVEGIN
General characteristics
Storage:
Active substance: 1 ml contains deproteyinizovanyy hemoderyvat blood of calves, which corresponds to 40 mg dry weight;
Excipients: sodium chloride, water for injections.
Form of issue
Product:
Solution for injection, 40 mg / mL to 2 mL (80 mg) capsules number 25; 5 ml (200 mg) in capsules number 5; 10 ml (400 mg) in capsules number 5 (packaging from in bulk manufacturer Nycomed Austria GmbH, Austria)
Farmhruppa
Pharmacological group.
Medications Alimentary tract and metabolism.
ATC code A16A X10.
Farmakolohycheskye properties
Pharmacological properties.
Pharmacodynamics.
Aktovegin contains only physiological substance with a molecular weight less than 5000 Daltons. At the molecular level, this drug helps accelerate the utilization of oxygen (increases resistance to hypoxia) and glucose, thereby improves energy metabolism. The total effect of these processes is to strengthen the energy state of the cell, especially in conditions of hypoxia and ischemia. Impact Actovegin the absorption and utilization of oxygen, and insulin-like activity of stimulating glucose transport and oxidation are important in the treatment of diabetic polyneuropathy. In patients with diabetes and diabetic polyneuropathy (stabbing pain, burning sensation, paresthesia, numbness in the lower extremities). Objectively reduced sensitivity disorders, improves mental health patients.
Pharmacokinetics
Pharmacokinetics.
Using pharmacokinetic methods can not study the pharmacokinetic properties (absorption, distribution and elimination of the active ingredients of the drug) Actovegin because it consists only of physiological components that are normally present in the body.
Indications for Application
Indication
Metabolic and circulatory disorders of the central nervous system:
- Ischemic stroke;
- Residual effects of hemorrhagic stroke;
- Head injuries;
- Encephalopathy different genesis.
Diabetic peripheral neuropathy.
Violation of peripheral arterial or venous circulation, angiopathy, including diabetic origin.
Ward 1 - 3 degrees (chemical, thermal, solar, radiation).
Healing wounds (ulcers of various etiologies, trophic disorders - bedsores (Dekubitus), disturbance of wound healing.
Radiation damage to the skin, mucous membranes, radiation neuropathy.
Method of application and dozы
Dosage and administration.
Aktovegin used intravenously (bolus drip), intra 5 - 20 ml per day.
Intramuscularly injected slowly, no more than 5 ml per day.
For intravenous drug solution diluted in 0.9% sodium chloride or 5% glucose solution. Non Actovegin final concentration - up to 2000 mg of dry matter per 250 ml solution.
Dosage:
a) The usual recommended dose:
Considering clinical symptoms, first introduced 5 - 10 ml intravenous or intra future - 5 ml intravenously or intramuscularly slowly every day or several times a week;
b) the dose depending on the indications for use:
In severe conditions
Intravenously administered 20 - 50 ml / day Actovegin for several days to achieve a pronounced clinical effect.
State of moderate or exacerbation of chronic diseases
5 - 20 ml / day intravenously or intramuscularly within 14 - 17 days.
The course is scheduled treatment
2 - 5 ml / day intravenously or intramuscularly within 4 - 6 weeks.
Number of introductions - from 1 to 3 times depending on the severity.
In dyabetychniy polyneuropathy:
Treatment begins with intravenous use of the drug in a dosage of 2 g per day 3 weeks, followed by the transition to tablets - 2-3 tablets 3 times a day for at least 4-5- months.
The drug is used to treat children:
- Newborns - 0.4 - 0.5 ml per 1 kg of body weight 1 time per day intramuscularly or intravenously;
- Children aged 1 to 3 years - 0.4 - 0.5 ml per 1 kg of body weight 1 time per day intramuscularly or intravenously;
- Children aged 3 to 6 years old - 0.25 - 0.4 ml per 1 kg of body weight 1 time per day intramuscularly or intravenously;
- Children aged 6 to 12 - 5 - 10 ml (200 - 400 mg), 1 per day intramuscularly or intravenously;
- Children aged 12 to 18 years - 10 - 15 ml (400 - 600 mg), 1 per day intramuscularly or intravenously.
Side эffektы
Adverse reactions.
The drug is generally well tolerated. In rare cases, allergic reactions are: fever, skin rash (polymorphic rash, hives, skin redness, itching sensation), anaphylaxis, angioedema shock. Possible fluctuations in blood pressure, dizziness, headache, general weakness. In such cases, drug treatment should be discontinued Aktovegin and apply symptomatic therapy.


Contraindications
Contraindication.
Hypersensitivity to the drug.
Interaction with the second lekarstvennыmy funds
Interaction with other medicinal products and other forms of interaction.
Data on Actovegin interactions with other drugs are not known.
Peredozyrovka
Overdose.
Today Aktovegin drug overdose are not known.
Features of application
Features of the application.
Intramuscular preferably administered no more than 5 ml, because the solution is hypertonic.
Due to the possibility of occurrence of anaphylactic recommended test injection (2 ml injected intramuscularly with the assessment of local and general reactions).
The solution for injection is compatible with isotonic sodium chloride solution and isotonic glucose. Actovegin is not recommended to mix with other solutions, other than the above.
Solution for injection has a yellowish hue, the intensity of which depends on the number of parties and the source material, but the color of the solution does not affect the efficiency and sensitivity to it.
Effects on ability to drive a car or operating machinery.
No effect.
Use during pregnancy and lactation.
Use of the drug Actovegin allowed for health reasons.
Children.
The drug used in pediatric practice.
Terms and conditions of storage and Term
Expiration date. 5 years.
Storage conditions.
Store in a dark place at a temperature below 25 ° C! Keep out of reach of children!
Terms and conditions otpuska
Conditions of supply:
prescription
Packaging
Packaging.
2 ml, 5 ml or 10 ml colorless glass ampoules. 25 vials of 2 ml in a cardboard box. 5 of 5 ml ampoules in a cardboard box. 5 vials of 10 ml in a cardboard box.
Producer of ego and addresses
Manufacturer country:
Ltd. "Kusum Pharm" m. Sumy, Ukraine

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