Tradename
APIZARTRON
Latin name
APISARTHRON
general characteristics
100 g of Apizarthron ointment contain standardized bee venom -0,003 g, methyl salicylate -10 g, alizolythiocyanate -1 g. Excipients: cetyl stearyl uril emulsified, sodium lauryl sulfate, medical vaseline, purified water
Form of issue
Ointment for external use.
Farmgroup
Means for topical application in joint and muscle pain.
Pharmacological properties
Combination drug for external use, the pharmacological properties of which are due to mutual potentiation of the therapeutic effects of each component. Standardized bee venom contains active ingredients that provide a multi-faceted therapeutic effect. The most important of them are melitin, histamine, gualuronidase, phospholipase. The second component of the ointment, methyl salicylate, belongs to the group of NSAIDs (non-steroidal anti-inflammatory drugs) that penetrate well through the skin. It provides anti-inflammatory and analgesic effects, which are enhanced by the action of the constituents of bee venom. The third component, alizolythiocyanate, has a locally irritating effect, which causes a local increase in skin temperature and an improvement in local circulation, which is enhanced by the influence of the constituents of bee venom - histamine and melitin. Improvement of local blood supply leads to better saturation of tissues with oxygen and accelerates the withdrawal from the focus of inflammation of toxic metabolic products that cause a sensation of pain.
Indications for use
Inflammatory and degenerative-dystrophic joint diseases (arthrosis and arthritis, including rheumatism); myalgia and pain in case of traumatic injuries of muscles, tendons, ligaments; neuralgic diseases (neuralgia, neuritis, sciatica, lumbago and radiculitis); peripheral disorders of the local circulation; As a heating agent in sports medicine.
Dosing and Administration
If the doctor has not appointed otherwise, a strip of ointment 3-5 cm long (depending on the area) is applied to the surface of the skin to be affected. The ointment is evenly distributed in a thin layer and awaits the appearance of a noticeable reaction (redness, sensation of heat), which occurs after 0.5-1 minutes, depending on the individual sensitivity of the organism. After that, slowly and intensely wipe the ointment into the skin. Treated body parts of the body is recommended to keep warm. As a rule, the drug is used 2-3 times a day until the symptoms disappear.
Side effects
When applied in accordance with the instruction on cases of intoxication to this time was not reported. Overdose can lead to skin irritation. In this case, the drug should be temporarily discontinued
Contraindications
Hypersensitivity to bee venom, salicylates and isothiocyanate; skin diseases; acute inflammation of the joints.
Interaction with other drugs
Not observed.
Overdose
When applied in accordance with the instruction on cases of intoxication to this time was not reported. Overdose can lead to skin irritation. In this case, the drug should be temporarily discontinued
Application features
Avoid contact with eyes, mucous membranes and open wounds. With renal failure, you can not apply ointment for a long time on large areas of the skin. It is not recommended to use the drug for infants and children under 6 years, for women during pregnancy and for breast-feeding
Terms and conditions of storage
Shelf life of the drug is 3 years. Do not use the product after the expiration date indicated on the packaging. Storage conditions. Keep at a temperature not higher than 25 ° C, out of the reach of children.
Leave conditions
Without recipe.
Packaging
Aluminum tubes of 20 g, 30 g, 50 g and 100 g of ointment
Manufacturer and its address
Esparma GmbH, Germany