Acyclovir - is an antiviral drug.
Indications & Dosage
Indications preparation:
Treatment of infections of the lips and face, HSV (Herpes labialis).
Acyclovir designed for outdoor use.
Adults and children over 12 years old to apply the Acyclovir 5 times a day for about 4 hour intervals, except at night. It is important to begin treatment as soon as possible at the beginning of infection, the best - during the prodromal period or erythema stage. You can start treatment and at later stages - papules or blisters.
The treatment lasts for at least 4 days. If healing has not occurred, it is possible to continue the treatment up to 10 dney.Esli symptoms do not disappear after 10 days of treatment, the patient should consult a doctor. It is necessary to wash your hands before and after using the Acyclovir , and avoid excessive rubbing or touching the affected parts with a towel to prevent the exacerbation or transmission.
Overdose
For oral or topical application of all the tube of Acyclovir Lipster adverse effects were found because of the minimal systemic exposure. In case of suspected overdose should seek medical help.
Side effects
In some patients, the application of a Acyclovir Cream may receive a temporary or a transient acute burning pain. Approximately 5% of patients occurred a slight drying and flaking of the skin. A small percentage of patients experienced erythema (redness) and itching. Very rarely reported cases of contact dermatitis after applying the Acyclovir . In carrying out these sensitivity tests cases were often associated with the components of the Acyclovir base, but not with isolated reports atsiklovirom.Imeyutsya immediate hypersensitivity reactions, including angioneurotic edema due topical acyclovir.
The preparation contains propylene glycol, which can cause skin irritation.
The preparation contains cetostearyl alcohol, which may cause local skin reactions (e.g. contact dermatitis).
Contraindications
Hypersensitivity to acyclovir, valacyclovir, propylene glycol or other componentsCream Acyclovir .
Interaction with other drugs and alcohol
You should not assign the drugCream with local cationic antiseptics.
Composition and Properties
active substance: aciclovir;
1 g of micronized acyclovir Acyclovir contains, based on 100% dry matter 50 mg
Other ingredients: white soft paraffin, liquid paraffin, cetostearyl alcohol (type A) is emulsified, propylene glycol, poloxamer, dimethicone, purified water.
Product: Acyclovir .
Pharmachologic effect:
Pharmacodynamics.
Acyclovir - is an antiviral drug that has a high in vitro activity against herpes simplex virus types I and II. The toxic activity against host organism cells minimalna.Popadaya in cells infected with herpes virus, acyclovir is phosphorylated to the active compound - acyclovir triphosphate. The first stage of this process depends on the availability virusokodovanoi thymidine kinase. Acyclovir triphosphate acts as an inhibitor and a substrate for the viral DNA polymerase, preventing further viral DNA synthesis without affecting normal cellular processes. Pharmacokinetics.
Pharmacokinetic studies have demonstrated a minimum level of systemic absorption of aciclovir following repeated topical application of the Acyclovir .
Storage: Store Cream should be in the original packaging at a temperature not exceeding 25 ° C. Do not freeze. Keep out of the reach of children.
